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SARS-CoV-2 IgG antibody test

SARS-CoV-2 IgG antibody test

SARS-CoV-2 IgG antibody test

The disposable serological SARS-CoV-2 IgG test is an enzyme immunoassay designed to identify IgG antibodies to the SARS-CoV-2 virus. Such tests allow a quantitative assessment of possible contact with the virus that causes COVID-19.
The IgG antibodies in the venous blood serum can be detected between 11 and 14 days after the first symptoms of the disease. They represent a “late-stage” infection accompanied by the humoral immune response that causes the antibody production confirming the contact with the SARS-CoV-2 virus. These antibodies can neutralize the virus, and their presence in blood confirms the immunity to COVID‑19.

Testing with the qualitative measuring of the concentration of neutralizing IgG antibodies to SARS-CoV-2 should be done for people who:

When is a test needed?

Convalescent patients should make the first test after at least two weeks after recovery. Vaccinated people should be tested 10-14 days after the first or second (or last) shot.
The test material is the patient’s venous blood (serum or plasma). The antibody conjugation reaction is performed on a supplied plastic plate with vitals covered with another antibody. The test results are calculated spectrophotometrically. The test doesn’t require any preparation. You don’t need to keep your stomach empty before the test.

Coronavirus antibody diagnosis

Positive results of serological tests suppose you are currently infected with or had recovered from SARS-CoV-2. But they can also confirm the cross-reaction of other coronavirus variants. False-positive results have about 3% of people vaccinated against influenza or having an autoimmune disease.
The highest accuracy is achieved through parallel testing for SARS-CoV-2 IgG and IgM antibodies. It would be 100% after the 10th day after the first symptoms and only 66% if the symptoms arose less than 10 days ago. For a final negation or confirmation of the SARS-CoV-2 infection, a polymerase chain reaction (PCR) test is needed.
Interpretation of test results
1. IgG negative (-):