en pl

Vitrotest SARS-CoV-2 IgM TK034

Vitrotest SARS-CoV-2 IgM TK034

SARS-CoV-2 IgM antibody test

The enzyme immunoassay kit is designed for the qualitative detection of IgM antibodies to the SARS-CoV-2 coronavirus. Detecting is based on a solid-phase type of enzyme immunoassay “IgM capture.” The IgM antibodies can be found after at least 7-11 days (9 days on average) after the first symptoms of the disease.
The patient’s venous blood serves as a sample for the test. Every test kit contains a vial on a special plate with an antigen on its bottom. The antigen incubates with the patient’s blood serum or plasma solution. Then, an added substrate solution changes color upon reaction. Finally, the results are determined spectrophotometrically.

When is an anti-SARS-CoV-2 test needed?

An antibody qualitative serological test is highly recommended for:

Description of the SARS-CoV-2 antibody assay

Serological test kits don’t identify specific neutralizing antibodies to the SARS CoV-2 coronavirus and do complement the PCR testing method. However, the serological diagnosis becomes vital at later stages of infection as the sensitivity of the molecular diagnosis descends due to decreasing the number of virus particles in the respiratory epithelium.
The IgM antibodies in the venous blood serum are “early-stage” consequences of the infection, so their presence can indicate an active phase of the disease. Therefore, a positive test result, the presence of IgM antibodies, does not always mean a final confirmation.
A test made too early can give a false-negative result during the so-called “serological gap” — a period when a specific humoral immune response is not being seen. Sometimes, even a positive test result can be caused by a passed or actual infection with coronavirus variants different from SARS-CoV-2, e.g., NL-63, HKU-1, or OC-43.
The SARS-CoV-2 IgM antibody test results should not be considered an ultimate indicator to confirm or deny the SARS-CoV-2 coronavirus disease and inflammatory processes in the human body.